I was getting a persistent error -21345 attempting to use Image Capture to scan from my Epson WF-2760 (a multifunction printer/scanner/copier) since upgrading to Golden Gate (macOS 27.0.1) on my iMac (2024 M4 chip). This same iMac was able to scan without issue just prior to the upgrade. (It was running Tahoe -- macOS 26.x)
I had done all of the basic troubleshooting and was about to write up a "help me" description of the problem to see if anybody here had any ideas that might help.
But as I was working through writing this up, I checked Settings > Printers & Scanners, saw the WF-2760, and thought "What if I remove and re-add it?" After removing it from the scanner list (but not the printer list) I relaunched Image Capture and it immediately began working.
The odd thing is that even though it no longer appears in the list of scanners in Settings, it is still recognized by Image Capture, and is still accessible by clicking the scanner icon in the upper right corner of Print Center, if that is open.
So… all of this is simply a note for future adventurers who may be having the same trouble I was having.
